{"id":24898,"date":"2025-11-27T11:59:47","date_gmt":"2025-11-27T06:29:47","guid":{"rendered":"https:\/\/icar-crri.in\/?p=24898"},"modified":"2025-11-27T17:27:51","modified_gmt":"2025-11-27T11:57:51","slug":"patent-for-a-next-generation-genome-editing-tool-granted-to-icar-crri","status":"publish","type":"post","link":"https:\/\/icar-crri.in\/hi\/patent-for-a-next-generation-genome-editing-tool-granted-to-icar-crri\/","title":{"rendered":"\u092d\u093e\u0915\u0943\u0905\u0928\u0941\u092a-\u0938\u0940\u0906\u0930\u0906\u0930\u0906\u0908 \u0915\u094b \u0905\u0917\u0932\u0940 \u092a\u0940\u0922\u093c\u0940 \u0915\u0947 \u091c\u0940\u0928\u094b\u092e \u090f\u0921\u093f\u091f\u093f\u0902\u0917 \u091f\u0942\u0932 \u0915\u093e \u092a\u0947\u091f\u0947\u0902\u091f \u092a\u094d\u0930\u0926\u093e\u0928 ","raw":"\u092d\u093e\u0915\u0943\u0905\u0928\u0941\u092a-\u0938\u0940\u0906\u0930\u0906\u0930\u0906\u0908 \u0915\u094b \u0905\u0917\u0932\u0940 \u092a\u0940\u0922\u093c\u0940 \u0915\u0947 \u091c\u0940\u0928\u094b\u092e \u090f\u0921\u093f\u091f\u093f\u0902\u0917 \u091f\u0942\u0932 \u0915\u093e \u092a\u0947\u091f\u0947\u0902\u091f \u092a\u094d\u0930\u0926\u093e\u0928 "},"content":{"rendered":"

\u092d\u093e\u0915\u0943\u0905\u0928\u0941\u092a-\u0938\u0940\u0906\u0930\u0906\u0930\u0906\u0908 \u0915\u094b \u0905\u0917\u0932\u0940 \u092a\u0940\u0922\u093c\u0940 \u0915\u0947 \u091c\u0940\u0928\u094b\u092e \u090f\u0921\u093f\u091f\u093f\u0902\u0917 \u091f\u0942\u0932 \u0915\u093e \u092a\u0947\u091f\u0947\u0902\u091f \u092a\u094d\u0930\u0926\u093e\u0928 <\/strong><\/p>\n

Cas9 \u0914\u0930 Cas12a \u091c\u0948\u0938\u0947 \u091c\u0940\u0928\u094b\u092e \u090f\u0921\u093f\u091f\u093f\u0902\u0917 \u091f\u0942\u0932 \u092c\u0939\u0941\u0924 \u092a\u094d\u0930\u092f\u094b\u0917 \u0939\u094b\u0924\u0947 \u0939\u0948\u0902, \u0932\u0947\u0915\u093f\u0928 \u0909\u0928\u0915\u093e \u092c\u0921\u093c\u0947 \u0906\u0915\u093e\u0930 (~1300 aa) \u0915\u0947 \u0915\u093e\u0930\u0923 \u092a\u0930\u093f\u0923\u093e\u092e \u0915\u092e \u092e\u093f\u0932\u0924\u093e \u0939\u0948\u0964 \u092d\u093e\u0915\u0943\u0905\u0928\u0941\u092a-\u0938\u0940\u0906\u0930\u0906\u0930\u0906\u0908 \u0915\u0947 \u0935\u0948\u091c\u094d\u091e\u093e\u0928\u093f\u0915\u094b\u0902 \u0928\u0947 \u090f\u0915 \u091b\u094b\u091f\u093e \u0935\u093f\u0915\u0932\u094d\u092a \u0935\u093f\u0915\u0938\u093f\u0924 \u0915\u093f\u092f\u093e \u0939\u0948: TnpB, \u090f\u0915 \u091f\u094d\u0930\u093e\u0902\u0938\u092a\u094b\u0938\u094b\u0928-\u090f\u0938\u094b\u0938\u093f\u090f\u091f\u0947\u0921 \u0928\u094d\u092f\u0942\u0915\u094d\u0932\u093f\u090f\u091c\u093c \u091c\u094b \u0915\u0947\u0935\u0932 408 \u0905\u092e\u0940\u0928\u094b \u090f\u0938\u093f\u0921 \u0932\u0902\u092c\u093e \u0939\u0948\u2014Cas9\/Cas12a \u0915\u0947 \u0906\u0915\u093e\u0930 \u0915\u093e \u090f\u0915-\u0924\u093f\u0939\u093e\u0908 \u0939\u0948\u0964 \u092d\u093e\u0915\u0943\u0905\u0928\u0941\u092a-\u0915\u0947\u0902\u0926\u094d\u0930\u0940\u092f \u091a\u093e\u0935\u0932 \u0905\u0928\u0941\u0938\u0902\u0927\u093e\u0928 \u0938\u0902\u0938\u094d\u0925\u093e\u0928 (\u0938\u0940\u0906\u0930\u0906\u0930\u0906\u0908), \u0915\u091f\u0915 \u0915\u094b \u092e\u0939\u0924\u094d\u0935\u092a\u0942\u0930\u094d\u0923 \u0928\u0935\u094b\u0928\u094d\u092e\u0947\u0937 \u0915\u093e\u0930\u094d\u092f \u201c\u092a\u094c\u0927\u094b\u0902 \u092e\u0947\u0902 \u0932\u0915\u094d\u0937\u093f\u0924 \u091c\u0940\u0928\u094b\u092e \u090f\u0921\u093f\u091f\u093f\u0902\u0917 \u0915\u0947 \u0932\u093f\u090f \u092a\u094d\u0930\u0923\u093e\u0932\u0940 \u0914\u0930 \u0924\u0930\u0940\u0915\u0947\u201d\u0915\u0947 \u0932\u093f\u090f \u092a\u0947\u091f\u0947\u0902\u091f \u0926\u093f\u092f\u093e \u0917\u092f\u093e \u0939\u0948, \u091c\u094b \u090f\u0915 \u091b\u094b\u091f\u0947 RNA-\u0917\u093e\u0907\u0921\u0947\u0921 \u0928\u094d\u092f\u0942\u0915\u094d\u0932\u093f\u090f\u091c\u093c TnpB \u092a\u0930 \u0915\u0947\u0902\u0926\u094d\u0930\u093f\u0924 \u0939\u0948\u0964
\n\u0938\u0940\u0906\u0930\u0906\u0930\u0906\u0908 \u0915\u0940 \u091f\u0940\u092e \u0928\u0947 \u092e\u094b\u0928\u094b\u0915\u0949\u091f\u094d\u0938 (\u091a\u093e\u0935\u0932) \u0914\u0930 \u0921\u093e\u0907\u0915\u0949\u091f\u094d\u0938 (\u0905\u0930\u0947\u092c\u093f\u0921\u094b\u092a\u094d\u0938\u093f\u0938) \u0926\u094b\u0928\u094b\u0902 \u092e\u0947\u0902 \u0909\u0932\u094d\u0932\u0947\u0916\u0928\u0940\u092f \u0909\u092a\u0932\u092c\u094d\u0927\u093f \u0939\u093e\u0938\u093f\u0932 \u0915\u0940, \u091c\u093f\u0938\u0938\u0947 69% \u0924\u0915 \u090f\u0921\u093f\u091f\u093f\u0902\u0917 \u092a\u094d\u0930\u092d\u093e\u0935\u0915\u093e\u0930\u093f\u0924\u093e \u092e\u093f\u0932\u0940\u0964 \u092f\u0939 \u092a\u094d\u0930\u0923\u093e\u0932\u0940 \u092a\u094c\u0927\u094b\u0902 \u092e\u0947\u0902 \u092c\u0939\u0941\u0935\u093f\u0927 \u090f\u0921\u093f\u091f\u093f\u0902\u0917 \u0914\u0930 \u092c\u0947\u0938 \u090f\u0921\u093f\u091f\u093f\u0902\u0917 \u0915\u094b \u092d\u0940 \u0938\u092e\u0930\u094d\u0925\u0928 \u0915\u0930\u0924\u093e \u0939\u0948\u0964
\n\u092f\u0939 \u092a\u0947\u091f\u0947\u0902\u091f\u0947\u0921 \u092e\u093f\u0928\u093f\u090f\u091a\u0930 TnpB \u092a\u094d\u0930\u0923\u093e\u0932\u0940 \u092a\u094c\u0927\u094b\u0902 \u092e\u0947\u0902 \u0915\u0941\u0936\u0932 \u0935\u093f\u0924\u0930\u0923, \u0938\u091f\u0940\u0915 \u0938\u0902\u092a\u093e\u0926\u0928 \u0914\u0930 \u0909\u0928\u094d\u0928\u0924 \u091c\u0940\u0928 \u0935\u093f\u0928\u093f\u092f\u092e\u0928 \u0915\u0947 \u0932\u093f\u090f \u0928\u090f \u0930\u093e\u0938\u094d\u0924\u0947 \u0916\u094b\u0932\u0924\u093e \u0939\u0948 \u091c\u093f\u0938\u0938\u0947 \u092d\u093e\u0930\u0924 \u0915\u094b \u0905\u0917\u0932\u0940 \u092a\u0940\u0922\u093c\u0940 \u0915\u0947 \u091c\u0940\u0928\u094b\u092e \u0907\u0902\u091c\u0940\u0928\u093f\u092f\u0930\u093f\u0902\u0917 \u092e\u0947\u0902 \u0938\u092c\u0938\u0947 \u0905\u0917\u094d\u0930\u0923\u0940 \u0930\u0939\u0947\u0917\u093e\u0964<\/p>\n\n\n\n
\"\"<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false,"raw":"

\u092d\u093e\u0915\u0943\u0905\u0928\u0941\u092a-\u0938\u0940\u0906\u0930\u0906\u0930\u0906\u0908 \u0915\u094b \u0905\u0917\u0932\u0940 \u092a\u0940\u0922\u093c\u0940 \u0915\u0947 \u091c\u0940\u0928\u094b\u092e \u090f\u0921\u093f\u091f\u093f\u0902\u0917 \u091f\u0942\u0932 \u0915\u093e \u092a\u0947\u091f\u0947\u0902\u091f \u092a\u094d\u0930\u0926\u093e\u0928 <\/strong><\/p>\r\nCas9 \u0914\u0930 Cas12a \u091c\u0948\u0938\u0947 \u091c\u0940\u0928\u094b\u092e \u090f\u0921\u093f\u091f\u093f\u0902\u0917 \u091f\u0942\u0932 \u092c\u0939\u0941\u0924 \u092a\u094d\u0930\u092f\u094b\u0917 \u0939\u094b\u0924\u0947 \u0939\u0948\u0902, \u0932\u0947\u0915\u093f\u0928 \u0909\u0928\u0915\u093e \u092c\u0921\u093c\u0947 \u0906\u0915\u093e\u0930 (~1300 aa) \u0915\u0947 \u0915\u093e\u0930\u0923 \u092a\u0930\u093f\u0923\u093e\u092e \u0915\u092e \u092e\u093f\u0932\u0924\u093e \u0939\u0948\u0964 \u092d\u093e\u0915\u0943\u0905\u0928\u0941\u092a-\u0938\u0940\u0906\u0930\u0906\u0930\u0906\u0908 \u0915\u0947 \u0935\u0948\u091c\u094d\u091e\u093e\u0928\u093f\u0915\u094b\u0902 \u0928\u0947 \u090f\u0915 \u091b\u094b\u091f\u093e \u0935\u093f\u0915\u0932\u094d\u092a \u0935\u093f\u0915\u0938\u093f\u0924 \u0915\u093f\u092f\u093e \u0939\u0948: TnpB, \u090f\u0915 \u091f\u094d\u0930\u093e\u0902\u0938\u092a\u094b\u0938\u094b\u0928-\u090f\u0938\u094b\u0938\u093f\u090f\u091f\u0947\u0921 \u0928\u094d\u092f\u0942\u0915\u094d\u0932\u093f\u090f\u091c\u093c \u091c\u094b \u0915\u0947\u0935\u0932 408 \u0905\u092e\u0940\u0928\u094b \u090f\u0938\u093f\u0921 \u0932\u0902\u092c\u093e \u0939\u0948\u2014Cas9\/Cas12a \u0915\u0947 \u0906\u0915\u093e\u0930 \u0915\u093e \u090f\u0915-\u0924\u093f\u0939\u093e\u0908 \u0939\u0948\u0964 \u092d\u093e\u0915\u0943\u0905\u0928\u0941\u092a-\u0915\u0947\u0902\u0926\u094d\u0930\u0940\u092f \u091a\u093e\u0935\u0932 \u0905\u0928\u0941\u0938\u0902\u0927\u093e\u0928 \u0938\u0902\u0938\u094d\u0925\u093e\u0928 (\u0938\u0940\u0906\u0930\u0906\u0930\u0906\u0908), \u0915\u091f\u0915 \u0915\u094b \u092e\u0939\u0924\u094d\u0935\u092a\u0942\u0930\u094d\u0923 \u0928\u0935\u094b\u0928\u094d\u092e\u0947\u0937 \u0915\u093e\u0930\u094d\u092f \u201c\u092a\u094c\u0927\u094b\u0902 \u092e\u0947\u0902 \u0932\u0915\u094d\u0937\u093f\u0924 \u091c\u0940\u0928\u094b\u092e \u090f\u0921\u093f\u091f\u093f\u0902\u0917 \u0915\u0947 \u0932\u093f\u090f \u092a\u094d\u0930\u0923\u093e\u0932\u0940 \u0914\u0930 \u0924\u0930\u0940\u0915\u0947\u201d\u0915\u0947 \u0932\u093f\u090f \u092a\u0947\u091f\u0947\u0902\u091f \u0926\u093f\u092f\u093e \u0917\u092f\u093e \u0939\u0948, \u091c\u094b \u090f\u0915 \u091b\u094b\u091f\u0947 RNA-\u0917\u093e\u0907\u0921\u0947\u0921 \u0928\u094d\u092f\u0942\u0915\u094d\u0932\u093f\u090f\u091c\u093c TnpB \u092a\u0930 \u0915\u0947\u0902\u0926\u094d\u0930\u093f\u0924 \u0939\u0948\u0964\r\n\u0938\u0940\u0906\u0930\u0906\u0930\u0906\u0908 \u0915\u0940 \u091f\u0940\u092e \u0928\u0947 \u092e\u094b\u0928\u094b\u0915\u0949\u091f\u094d\u0938 (\u091a\u093e\u0935\u0932) \u0914\u0930 \u0921\u093e\u0907\u0915\u0949\u091f\u094d\u0938 (\u0905\u0930\u0947\u092c\u093f\u0921\u094b\u092a\u094d\u0938\u093f\u0938) \u0926\u094b\u0928\u094b\u0902 \u092e\u0947\u0902 \u0909\u0932\u094d\u0932\u0947\u0916\u0928\u0940\u092f \u0909\u092a\u0932\u092c\u094d\u0927\u093f \u0939\u093e\u0938\u093f\u0932 \u0915\u0940, \u091c\u093f\u0938\u0938\u0947 69% \u0924\u0915 \u090f\u0921\u093f\u091f\u093f\u0902\u0917 \u092a\u094d\u0930\u092d\u093e\u0935\u0915\u093e\u0930\u093f\u0924\u093e \u092e\u093f\u0932\u0940\u0964 \u092f\u0939 \u092a\u094d\u0930\u0923\u093e\u0932\u0940 \u092a\u094c\u0927\u094b\u0902 \u092e\u0947\u0902 \u092c\u0939\u0941\u0935\u093f\u0927 \u090f\u0921\u093f\u091f\u093f\u0902\u0917 \u0914\u0930 \u092c\u0947\u0938 \u090f\u0921\u093f\u091f\u093f\u0902\u0917 \u0915\u094b \u092d\u0940 \u0938\u092e\u0930\u094d\u0925\u0928 \u0915\u0930\u0924\u093e \u0939\u0948\u0964\r\n\u092f\u0939 \u092a\u0947\u091f\u0947\u0902\u091f\u0947\u0921 \u092e\u093f\u0928\u093f\u090f\u091a\u0930 TnpB \u092a\u094d\u0930\u0923\u093e\u0932\u0940 \u092a\u094c\u0927\u094b\u0902 \u092e\u0947\u0902 \u0915\u0941\u0936\u0932 \u0935\u093f\u0924\u0930\u0923, \u0938\u091f\u0940\u0915 \u0938\u0902\u092a\u093e\u0926\u0928 \u0914\u0930 \u0909\u0928\u094d\u0928\u0924 \u091c\u0940\u0928 \u0935\u093f\u0928\u093f\u092f\u092e\u0928 \u0915\u0947 \u0932\u093f\u090f \u0928\u090f \u0930\u093e\u0938\u094d\u0924\u0947 \u0916\u094b\u0932\u0924\u093e \u0939\u0948 \u091c\u093f\u0938\u0938\u0947 \u092d\u093e\u0930\u0924 \u0915\u094b \u0905\u0917\u0932\u0940 \u092a\u0940\u0922\u093c\u0940 \u0915\u0947 \u091c\u0940\u0928\u094b\u092e \u0907\u0902\u091c\u0940\u0928\u093f\u092f\u0930\u093f\u0902\u0917 \u092e\u0947\u0902 \u0938\u092c\u0938\u0947 \u0905\u0917\u094d\u0930\u0923\u0940 \u0930\u0939\u0947\u0917\u093e\u0964\r\n\r\n\r\n\r\n
\"\"<\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>"},"excerpt":{"rendered":"Patent for a Next-Generation Genome Editing tool granted to ICAR-CRRI Genome editing tools like Cas9 and Cas12a are widely used, but their large size (~1300 aa) limits delivery. Scientists at ICAR-CRRI have developed a compact alternative: TnpB, a transposon-associated nuclease only 408 amino acids long\u2014one-third the size of Cas9\/Cas12a. ICAR\u2013Central Rice Research Institute (CRRI), Cuttack, [...]","protected":false,"raw":""},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_hi_post_content":"

\u092d\u093e\u0915\u0943\u0905\u0928\u0941\u092a-\u0938\u0940\u0906\u0930\u0906\u0930\u0906\u0908 \u0915\u094b \u0905\u0917\u0932\u0940 \u092a\u0940\u0922\u093c\u0940 \u0915\u0947 \u091c\u0940\u0928\u094b\u092e \u090f\u0921\u093f\u091f\u093f\u0902\u0917 \u091f\u0942\u0932 \u0915\u093e \u092a\u0947\u091f\u0947\u0902\u091f \u092a\u094d\u0930\u0926\u093e\u0928 <\/strong><\/p>\r\nCas9 \u0914\u0930 Cas12a \u091c\u0948\u0938\u0947 \u091c\u0940\u0928\u094b\u092e \u090f\u0921\u093f\u091f\u093f\u0902\u0917 \u091f\u0942\u0932 \u092c\u0939\u0941\u0924 \u092a\u094d\u0930\u092f\u094b\u0917 \u0939\u094b\u0924\u0947 \u0939\u0948\u0902, \u0932\u0947\u0915\u093f\u0928 \u0909\u0928\u0915\u093e \u092c\u0921\u093c\u0947 \u0906\u0915\u093e\u0930 (~1300 aa) \u0915\u0947 \u0915\u093e\u0930\u0923 \u092a\u0930\u093f\u0923\u093e\u092e \u0915\u092e \u092e\u093f\u0932\u0924\u093e \u0939\u0948\u0964 \u092d\u093e\u0915\u0943\u0905\u0928\u0941\u092a-\u0938\u0940\u0906\u0930\u0906\u0930\u0906\u0908 \u0915\u0947 \u0935\u0948\u091c\u094d\u091e\u093e\u0928\u093f\u0915\u094b\u0902 \u0928\u0947 \u090f\u0915 \u091b\u094b\u091f\u093e \u0935\u093f\u0915\u0932\u094d\u092a \u0935\u093f\u0915\u0938\u093f\u0924 \u0915\u093f\u092f\u093e \u0939\u0948: TnpB, \u090f\u0915 \u091f\u094d\u0930\u093e\u0902\u0938\u092a\u094b\u0938\u094b\u0928-\u090f\u0938\u094b\u0938\u093f\u090f\u091f\u0947\u0921 \u0928\u094d\u092f\u0942\u0915\u094d\u0932\u093f\u090f\u091c\u093c \u091c\u094b \u0915\u0947\u0935\u0932 408 \u0905\u092e\u0940\u0928\u094b \u090f\u0938\u093f\u0921 \u0932\u0902\u092c\u093e \u0939\u0948\u2014Cas9\/Cas12a \u0915\u0947 \u0906\u0915\u093e\u0930 \u0915\u093e \u090f\u0915-\u0924\u093f\u0939\u093e\u0908 \u0939\u0948\u0964 \u092d\u093e\u0915\u0943\u0905\u0928\u0941\u092a-\u0915\u0947\u0902\u0926\u094d\u0930\u0940\u092f \u091a\u093e\u0935\u0932 \u0905\u0928\u0941\u0938\u0902\u0927\u093e\u0928 \u0938\u0902\u0938\u094d\u0925\u093e\u0928 (\u0938\u0940\u0906\u0930\u0906\u0930\u0906\u0908), \u0915\u091f\u0915 \u0915\u094b \u092e\u0939\u0924\u094d\u0935\u092a\u0942\u0930\u094d\u0923 \u0928\u0935\u094b\u0928\u094d\u092e\u0947\u0937 \u0915\u093e\u0930\u094d\u092f \u201c\u092a\u094c\u0927\u094b\u0902 \u092e\u0947\u0902 \u0932\u0915\u094d\u0937\u093f\u0924 \u091c\u0940\u0928\u094b\u092e \u090f\u0921\u093f\u091f\u093f\u0902\u0917 \u0915\u0947 \u0932\u093f\u090f \u092a\u094d\u0930\u0923\u093e\u0932\u0940 \u0914\u0930 \u0924\u0930\u0940\u0915\u0947\u201d\u0915\u0947 \u0932\u093f\u090f \u092a\u0947\u091f\u0947\u0902\u091f \u0926\u093f\u092f\u093e \u0917\u092f\u093e \u0939\u0948, \u091c\u094b \u090f\u0915 \u091b\u094b\u091f\u0947 RNA-\u0917\u093e\u0907\u0921\u0947\u0921 \u0928\u094d\u092f\u0942\u0915\u094d\u0932\u093f\u090f\u091c\u093c TnpB \u092a\u0930 \u0915\u0947\u0902\u0926\u094d\u0930\u093f\u0924 \u0939\u0948\u0964\r\n\u0938\u0940\u0906\u0930\u0906\u0930\u0906\u0908 \u0915\u0940 \u091f\u0940\u092e \u0928\u0947 \u092e\u094b\u0928\u094b\u0915\u0949\u091f\u094d\u0938 (\u091a\u093e\u0935\u0932) \u0914\u0930 \u0921\u093e\u0907\u0915\u0949\u091f\u094d\u0938 (\u0905\u0930\u0947\u092c\u093f\u0921\u094b\u092a\u094d\u0938\u093f\u0938) \u0926\u094b\u0928\u094b\u0902 \u092e\u0947\u0902 \u0909\u0932\u094d\u0932\u0947\u0916\u0928\u0940\u092f \u0909\u092a\u0932\u092c\u094d\u0927\u093f \u0939\u093e\u0938\u093f\u0932 \u0915\u0940, \u091c\u093f\u0938\u0938\u0947 69% \u0924\u0915 \u090f\u0921\u093f\u091f\u093f\u0902\u0917 \u092a\u094d\u0930\u092d\u093e\u0935\u0915\u093e\u0930\u093f\u0924\u093e \u092e\u093f\u0932\u0940\u0964 \u092f\u0939 \u092a\u094d\u0930\u0923\u093e\u0932\u0940 \u092a\u094c\u0927\u094b\u0902 \u092e\u0947\u0902 \u092c\u0939\u0941\u0935\u093f\u0927 \u090f\u0921\u093f\u091f\u093f\u0902\u0917 \u0914\u0930 \u092c\u0947\u0938 \u090f\u0921\u093f\u091f\u093f\u0902\u0917 \u0915\u094b \u092d\u0940 \u0938\u092e\u0930\u094d\u0925\u0928 \u0915\u0930\u0924\u093e \u0939\u0948\u0964\r\n\u092f\u0939 \u092a\u0947\u091f\u0947\u0902\u091f\u0947\u0921 \u092e\u093f\u0928\u093f\u090f\u091a\u0930 TnpB \u092a\u094d\u0930\u0923\u093e\u0932\u0940 \u092a\u094c\u0927\u094b\u0902 \u092e\u0947\u0902 \u0915\u0941\u0936\u0932 \u0935\u093f\u0924\u0930\u0923, \u0938\u091f\u0940\u0915 \u0938\u0902\u092a\u093e\u0926\u0928 \u0914\u0930 \u0909\u0928\u094d\u0928\u0924 \u091c\u0940\u0928 \u0935\u093f\u0928\u093f\u092f\u092e\u0928 \u0915\u0947 \u0932\u093f\u090f \u0928\u090f \u0930\u093e\u0938\u094d\u0924\u0947 \u0916\u094b\u0932\u0924\u093e \u0939\u0948 \u091c\u093f\u0938\u0938\u0947 \u092d\u093e\u0930\u0924 \u0915\u094b \u0905\u0917\u0932\u0940 \u092a\u0940\u0922\u093c\u0940 \u0915\u0947 \u091c\u0940\u0928\u094b\u092e \u0907\u0902\u091c\u0940\u0928\u093f\u092f\u0930\u093f\u0902\u0917 \u092e\u0947\u0902 \u0938\u092c\u0938\u0947 \u0905\u0917\u094d\u0930\u0923\u0940 \u0930\u0939\u0947\u0917\u093e\u0964\r\n\r\n\r\n\r\n
\"\"<\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>","_hi_post_name":"patent-for-a-next-generation-genome-editing-tool-granted-to-icar-crri","_hi_post_excerpt":"","_hi_post_title":"\u092d\u093e\u0915\u0943\u0905\u0928\u0941\u092a-\u0938\u0940\u0906\u0930\u0906\u0930\u0906\u0908 \u0915\u094b \u0905\u0917\u0932\u0940 \u092a\u0940\u0922\u093c\u0940 \u0915\u0947 \u091c\u0940\u0928\u094b\u092e \u090f\u0921\u093f\u091f\u093f\u0902\u0917 \u091f\u0942\u0932 \u0915\u093e \u092a\u0947\u091f\u0947\u0902\u091f \u092a\u094d\u0930\u0926\u093e\u0928 ","_en_post_content":"

Patent for a Next-Generation Genome Editing tool granted to ICAR-CRRI <\/strong><\/p>\r\nGenome editing tools like Cas9 and Cas12a are widely used, but their large size (~1300 aa) limits delivery. Scientists at ICAR-CRRI have developed a compact alternative: TnpB, a transposon-associated nuclease only 408 amino acids long\u2014one-third the size of Cas9\/Cas12a.\r\nICAR\u2013Central Rice Research Institute (CRRI), Cuttack, has been granted a patent for its breakthrough innovation \u201cSystems and Methods for Targeted Genome Editing in Plants\u201d, centred on a miniature RNA-guided nuclease TnpB.\r\nThe CRRI team demonstrated its high performance in both monocots (rice) and dicots (Arabidopsis), achieving up to 69% editing efficiency. The system also supports multiplex editing and base editing in plants.\r\nThis patented miniature TnpB system opens new avenues for efficient delivery, precise editing, and advanced gene regulation in plants\u2014positioning India at the forefront of next-generation genome engineering.\r\n\r\n\r\n\r\n
\"\"<\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>","_en_post_name":"patent-for-a-next-generation-genome-editing-tool-granted-to-icar-crri","_en_post_excerpt":"","_en_post_title":"Patent for a Next-Generation Genome Editing tool granted to ICAR-CRRI ","edit_language":"hi","footnotes":""},"categories":[28],"tags":[],"class_list":["post-24898","post","type-post","status-publish","format-standard","hentry","category-news"],"_links":{"self":[{"href":"https:\/\/icar-crri.in\/hi\/wp-json\/wp\/v2\/posts\/24898","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/icar-crri.in\/hi\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/icar-crri.in\/hi\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/icar-crri.in\/hi\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/icar-crri.in\/hi\/wp-json\/wp\/v2\/comments?post=24898"}],"version-history":[{"count":3,"href":"https:\/\/icar-crri.in\/hi\/wp-json\/wp\/v2\/posts\/24898\/revisions"}],"predecessor-version":[{"id":24930,"href":"https:\/\/icar-crri.in\/hi\/wp-json\/wp\/v2\/posts\/24898\/revisions\/24930"}],"wp:attachment":[{"href":"https:\/\/icar-crri.in\/hi\/wp-json\/wp\/v2\/media?parent=24898"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/icar-crri.in\/hi\/wp-json\/wp\/v2\/categories?post=24898"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/icar-crri.in\/hi\/wp-json\/wp\/v2\/tags?post=24898"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}